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Here, we showed that exposure to the smoke of a tobacco-free cigarette decreases the GSH/GSSG ratio in relation to the control, confirming that the tobacco-free cigarette causes oxidative stress in the lung

With repeated exposure to tobacco smoke, this irritation may become more noticeable or persistent

So, lets get to the review

Retrieved December 10, 2020, from Dwedar, I., Ruby, D., & Mostafa, A

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A longitudinal study of persistent smoking among HIV-positive gay and bisexual men in primary relationships