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Topical Analgesics Topical analgesics including lidocaine patches and creams, capsaicin, and topical NSAIDs, have not been studied in patients with cirrhosis, but are generally considered safe given minimal systemic absorption [62, 63]

(181) conducted a study involving 15 postmenopausal women with moderate OSAHS, administering estrogen (either oral CEE at 0.625 mg/d, estradiol valerate at 1 mg/d, or transdermal estradiol at 8 mg/week) in conjunction with combined progesterone (MPA at 2.510 mg/d) over a period of 50 days, and found no significant reduction in sleep-disordered breathing events

Arzi A, Olapour S, Yaghooti H, Sistani Karampour N

doi: 10.1038/s41586-022-05299-4 40 ChenW.TeoJ

ArticlePubMedPMC [65] Ring M, Ai D, Maker-Clark G, Sarazen R

Risk of total and aggressive prostate cancer and pesticide use in the agricultural health study