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And market heavyweight Juul is the subject of multiple federal investigations and almost 200 individual lawsuits.

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It followed a total of 5.6 million people to see who developed coronary heart disease and 7.3 million people for stroke

Reynolds Tobacco Co., said, Once the report is issued, we look forward to reviewing it and seeing what policy recommendations the GAO presents to effectively deal with this problem. Bob Bannon, director of investor relations with the Lorrilard tobacco company, declined to comment on the GAO report

To estimate the proportion of cancer deaths attributable to smoking, the researchers used a standard formula to calculate the fraction of cases of specific cancer types that would not have occurred if there were no smoking