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Structural Basis for GLP-1 Receptor Activation by LY3502970, an Orally Active Nonpeptide Agonist
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Inspired by rat amylin, which is less prone to dimerize, the enhanced stability of pramlintide compared to human amylin was achieved by introducing three amino acid substitutions (pro25,28,29) into the sequence of human amylin ( Table 1 )

Clinical Cardiology

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