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Pancreatitis can develop because of the stimulating effect of the medication on the islet cells of the pancreas that produce insulin

Kutcher SA, Brophy JM, Banack HR, Kaufman JS, Samuel M

Several ongoing clinical trials are investigating incretin-based therapies for alcohol use disorder, tobacco use disorder, and opioid use disorder

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Nassif, S

This is why maintaining adequate protein intake (at least 1 gram per kilogram of goal body weight daily) is critical at the maximum dose