3 harmful substances found in cigarettes What Chemicals Are Cigarettes? PPT - Smoking and Tobacco
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[49] Tentative evidence indicates that health warnings on vaping products may influence users to give up vaping

doi:10.1177/1091581815618935

Oxford University Press: 3337

Nicotine as a sedative Nicotine also has an indirect impact on the brain

However, as you build up more of a tolerance to nicotine over time, you will often require a higher dose to enjoy the same effects

this is the lowest proportion of current smokers since records started in 2011