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2:42m watch People started to get worried in the 40s because lung cancer was spiking
In line with the hypothesis that epithelium from control smokers is better protected against cigarette smoke-induced changes in mitochondrial function, OXPHOS complex levels were not (persistently) higher in PBECs from smokers with normal lung function than from never-smokers, although OXPHOS complex II, III and VF1 were increased upon long-term CSE exposure in BEAS-2B
Bibcode:2014JAMA..311..183N

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Direct determination of cotinine-N-glucuronide in urine using thermospray liquid chromatography/mass spectrometry

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