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Measuring fatigue with a single question, while practical, might miss aspects of the experience

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The Mayo Clinic reports side effects that include fatigue, drowsiness, reduced appetite, diarrhea and dry mouth

Unit risks are upper bound toxicological estimates that may overestimate true potency.42 If large volumes of carbonyls are generated by EC use under circumstances not normally tolerated by humans (eg, dry puffs), then the apparent high-risk levels may not be reached.40 A simple aggregation does not account for enhancement by synergystic interactions between components (but there may also be antagonistic interactions)

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