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They can be used as a possible alternative to tobacco smoking and some results showed that they can play an interesting role as a smoking cessation aid [1]

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They found a significant reduction of 3.6 mmHg in SBP and HR decreased by 7 beats/min in 19 women who had ceased smoking

The weight of evidence indicates that chronic exposure to tobacco smoke alters the immune and inflammatory processes in the lung causing changes in humoral and cell-mediated immune responses (Figure 3) [99]

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