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But over time and continued use, the brains circuitry adapts to increasing concentrations of a dopamine-releasing substance such as nicotine or cocaine

"It feels like we have put all our eggs in one basket and said 'this is the way to tackle cigarette smoking' and I feel we have neglected children and young people, by sort of embracing something almost too much without the real proper thought." Prof Ann McNeil was one of the co-authors of the original 2015 report and told the BBC that the advice was based on the literature at the time and what was known about what the products contained

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Smoking significantly increases the risk of heart disease, stroke , and cancers in multiple organs

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