1 or 2 cigarettes a day Just 1-2 cigarettes/day before during pregnancy linked to major newborn health problems smoking 1 or 2 cigarettes
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Histones: the critical players in innate immunity

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An increase in acetylated histone H4 was found in current smokers, while patients with COPD who had stopped smoking had increased histone H3 acetylation, suggesting that the persistent inflammation in the lungs of the COPD patients after smoking cessation may be regulated by histone H3 acetylation [29]

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"Cigar and pipe smoking and cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)"
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