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A study using an animal model exposed to THS under conditions that mimic exposure of humans suggests there are adverse effects of THS on liver, lung, skin healing, and behavior.In this study, THS delayed wound healing, increased hyperactivity on behavior tests, increased non-alcoholic fatty liver disease predisposing cirrhosis and cancer in liver, and stimulated excess collagen and cytokines production in lungs emulating inflammation-induced diseases such as COPD or asthma

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Publication occurred within 2 years of data collection for 31% of studies, within 2 to 5 years for 45%, and more than 5 years for 10%and was not reported for 14% of studies