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ZugnoAIFragaDBDe LucaRDGhedimFVDerozaPFCiprianoALet alChronic exposure to cigarette smoke during gestation results in altered cholinesterase enzyme activity and behavioral deficits in adult rat offspring: potential relevance to schizophrenia

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And the resulting sleep deficit can make it difficult to stay away from cigarettes

Actual absorption varies based on smoking duration, tobacco type, and individual factors