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3, 3-diindolylmethane, a natural aryl hydrocarbon receptor agonist, alleviates ulcerative colitis by enhancing glycolysis-lactate-STAT3 and TIP60 signals-mediated Treg differentiation

As a general procedure, the investigators directly performing the experimental procedures were not blinded to the group allocation, but data analyses by senior authors were largely conducted independently to avoid potential bias

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Keywords: obesity, glucagon, GLP-1, GIP, dual-agonist therapies, triple agonist therapies Obesity Obesity is a complex, chronic, miscellaneous disease marked by excessive fat accumulation that significantly impacts health with an alarming rise in global prevalence, affecting over 890 million adults by the year 2022