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This method is typically performed in a clinical setting

Because of secondhand smoke, tobacco use can also expose nonsmokers to carcinogens and other toxic chemicals

"Nornicotine nitrosation in saliva and its relation to endogenous synthesis of N'-nitrosonornicotine in humans"

So while smoking seems to be decreasing in the US, theres still a huge customer base for tobacco its just shifting elsewhere

A premarket review should establish that the products are significantly safer than cigarettes and pose no excessive risks