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Int J Radiat Oncol Biol Phys 121(4):951-962, 2025
Date modified: 8 April 2026 First published: May 2020
The GPI gene is located on chromosome 19q13.11 spanning 40 kb and composed of 20 exons that generate seven alternatively spliced mRNAs that collectively encode five protein isoforms
Pathologically activated astrocytes exhibit disrupted intracellular signaling or metabolic homeostasis, impairing EAAT2 transcription, translation, or trafficking
Anand B
Heintz L, Meyer-Schwesinger C
