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A content analysis of the Camel Snus break free campaign suggested that some of the messages could be taken to refer to a change in use of smokeless tobacco while other messages could be a call for an adolescent to act independently from parents or from the mainstream youth or adult population. For instance, some adolescents may readily relate to the rebellious tone of advertisements, such as Keep making noise or Be hear not hearded.3 1

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He noted the recent proliferation of nicotine pouches and heated tobacco products, particularly among younger Hoosiers

It is unclear what this change in expression represents as there were no differences in histopathology or pathology-related genes between responders, regardless of nicotine exposure

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