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[47] The first large outbreak of syphilis in Europe occurred in 14941495 among the army of Charles VIII during its invasion of Naples

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This spark is created by applying pressure (friction) say, the push of a button or turn of a wheel against a crystal that contains electricity

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Tobacco Mosaic Virus Uses In Pharmaceutical Research Tobacco Mosaic Virus Uses in Pharmaceutical Research By Michael Itschner II Introduction The Tobacco Mosaic Virus (TMV) has been well researched since it has been defined a virus in 1898 by Martinus Beijerinck.[1] TMV has been used as a model virus for a teaching tool in biology classes and as a scaffold for drug delivery mechanisms.[6] Since there has been much research done on this virus previously, the structure of TMV has been extensively studied and is well understood.[5] The scaffolding of this virus is of particular interest because its protein base serves as a template for precise targeting of surface groups on cells