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Added flavouring does not remove the underlying herbal blend, paper, filter characteristics or the effects of combustion

Its hard to isolate the effects of nicotine from those of tobacco, but animal and laboratory studies suggest nicotine could be responsible for cognitive and behavioral changes including addiction in people who begin using it as youths

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In general, treatment methods include surgery, chemotherapy, radiation therapy, targeted therapy, or a combination of any of these treatments

Aside from tobacco, additives, and filters, cigarettes are also comprised of the paper on which all these ingredients have been rolled

* Correspondence: Nicols Serafn-Higuera, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers