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Velo was chosen because it had the largest brand market share of nicotine pouches (~95% of the nicotine pouch market in Pakistan in 2023),12 it was being heavily promoted in Pakistan at the time and it had a number of brand variants on the market which allowed us to explore the differences in flavours and nicotine across brand variants within a brand

On the issue of the boundaries around UPFs, the NOVA classification was developed by a scientist for scientists, but fortunately, there are really good published, peer-reviewed demonstrations that that classification system can be adapted to work for policymakers

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42, 56 In the postoperative pain setting, the administration of nicotine produces analgesia in nicotine nave participants and produces little or no analgesic effect in smokers

By comparison, Zyn products often require saliva to moisten the pouch before nicotine delivery becomes more noticeable