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Significantly, smoking alters the levels of interleukin-1 and interleukin-6 in humans 35

Evaluation of smoking cessation and IBS at follow-up at 1 year Cessation treatment was successful in 27 (40.3%) of 67 smokers with IBS who had received smoking cessation treatment, of whom 62 had no change in their recurrent abdominal pain and were again evaluated as being IBS(+)

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ENDS, known colloquially as e-cigarettes or vapes, work by heating a liquid solution containing nicotine, flavors, solvents like propylene glycol (PG) and vegetable glycerin (VG), and other additives to generate an inhalable aerosol

However, these studies had limitations, such as low patient numbers or study design concerns, resulting in controversial conclusions

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