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Description
Additionally, a calcitriol-elicited downregulation of the anti-apoptotic BCL2 and BCLXL and overexpression of the pro-apoptotic BAX, BAK , and BAD genes have also been described [147]
Henry A

People can put on a nicotine patch as soon as they stop smoking

Not just lung cancer, tobacco leads to bladder, cervix, colon & rectum, esophagus, kidney & renal pelvis, lungs, bronchi, trachea, blood, stomach, and liver cancer

Oh, and while we're at it, take a look at these long-ago ads for the supposed health benefits of morphine, cocaine, and amphetamines
Short answer: Scientists dont know much, but have raised red flags