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Clinical trials have demonstrated hemoglobin A1c reductions of approximately 2% in diabetes patients, with weight loss ranging from 7-11% in diabetes trials (SURPASS) and 15-21% in obesity trials (SURMOUNT), depending on the dose administered and patient population

The satiety index is based on Holts original research, which measured hunger over two hours in controlled settings

HGH directly counteracts the catabolic pressure of caloric restriction by promoting protein synthesis and reducing protein breakdown