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Were not here to judge

13 One review found an increase in serious adverse events with varenicline in unselected smokers (RR, 1.25 [95% CI, 1.04-1.49]

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These disparate findings may result from differences in rat strains as Jobson, Ng, and colleagues studied Sprague-Dawley rats, while Cadoni and colleagues noted a decrease in firing rate in Lewis rats, with no significant change in Fisher rats

This ignorance wasn't calculated but had the same hurtful effect