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She was subsequently offered the role of Maid Marian in Kevin Costners Robin Hood: Prince of Thieves but turned it down because she had met Sean Penn (on the set of State of Grace in 1990, the year after he divorced his first wife, Madonna), and was pregnant with his child

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European journal of pharmacology 498 , 279286, (2004)

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Smoking, and in turn chain-smoking, can cause shortness of breath, coughing, and fatigue

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