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After adjustment for multiple confounders, young adults who currently used e-cigarettes every day were 42% more likely to report sleep deprivation than those who never used e-cigarettes, a difference that was statistically significant

This study found that sidestream smoke is nearly four times more toxic than mainstream smoke per metric gramme

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Using e-cigarettes has also been shown to have a strong association with becoming a smoker in the future

101:3: 348-361 Ecstasy, the serotonin syndrome, and neuroleptic malignant syndrome a possible link