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The reduced digestive impact of NRTs likely results from: Lower peak nicotine levels compared to cigarettes or snus More gradual nicotine absorption rates Absence of additional tobacco compounds that may affect digestion Steady release formulations (especially patches) that prevent nicotine spikes For people quitting smoking who are concerned about constipation, transitioning through nicotine pouches or gum before eliminating nicotine completely might help manage digestive changes more comfortably

Nadel JA, Comroe JH Jr

Roll-up papers with more micro-holes (higher porosity) burn faster and offer lower nicotine doses

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The evidence also suggests that smoking cessation may reduce the risk of other adverse outcomes, including placental abruption, preterm delivery, stillbirth, and early menopause