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nAChRs might be present in the neuronal terminals that innervate the cardiac muscle, although it has been described that only glutamatergic neurons and peripheral crustacean cardioactive peptide neurons reach the Drosophila heart (Dulcis and Levine, 2005)

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Beyond the 14% of Americans smoking cigarettes, 3.8% are smoking cigars, 2.8% are using e-cigarettes or vaping, 2.1% use smokeless tobacco products, and 1% are using pipes

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