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To explain the discrepancy in the results, it was proposed that the deleterious effect of smoking on AD may have been masked by the fact that subjects who would have subsequently developed AD had either died or left the study due to other co-morbidities 24,25

Harm reduction is the concept that it is more practical to reduce the harm associated with the use of certain products rather than attempting to eliminate it completely through ineffective bans or punitive levels of taxation