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miRNAs are small non-coding RNAs that regulate gene expression through the induction of mRNA degradation and inhibition of translation
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Because it can be hard to establish the brand of cigarette a person smoked decades ago, the strategy often succeeds

Repeated measures ANOVA was used for comparisons of multiple groups over more than one time point, and two-way interaction terms were created for treatment group and time

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However, results are highly variable
