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The discrepancy in findings can create a significant problem when addressing regulatory or clinical questions posed by the expansion of e-cigarette use

I am concerned about what their priorities will be

Given the limited number of available studies, the lack of a control group in almost all current studies, the absence of long-term prospective data, and the relatively recent introduction of these products, the long-term implications of nicotine pouches in oral carcinogenesis remain unclear

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