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Brain lesions disrupting addiction map to a common human brain circuit

These early metabolic changes may remain undiagnosed for years

Studies show that smoking leads to brain atrophy, especially in areas critical for memory, learning and decision-making, such as the hippocampus and frontal cortex. The toxic chemicals in cigarettes, such as nicotine and carbon monoxide, also restrict blood flow to the brain therefore reduce oxygen supply to brain cells, explains the neurologist

Figure 2 The Purchase Price of a Pack of Cigarettes Includes Markups and Taxes Source: CDTFAs Tax Guide for Tobacco Products , fiscal year 201819 other tobacco products tax calculations, California city and county sales and use tax rates, federal law, and auditor observation

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She established herself as a powerhouse of both classical drama and sharp comedy