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These results demonstrate that quitting smoking is much more effective at reducing disease than 'cutting down' the number of cigarettes smoked, Dr Weber said

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thus, it is important to keep both on the differential as we better understand the potential interplay of the disease presentations

Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines 31 for each of our systematic reviews, we identified studies reporting relative risk (RR) of incidence or mortality from each of the 36 selected outcomes for smokers compared with nonsmokers

Tobacco advertising, promotion and sponsorship are banned in Canada and warnings on cigarette packs have existed since 1972

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