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25 Klatsky and Armstrong showed a tripling risk of developing alcoholic cirrhosis when smoking a pack or more of cigarettes per day as compared with nonsmokers in 128,934 individuals

Interventions for Tobacco Smoking Cessation in Adults, Including Pregnant Persons

Early intrauterine exposure to tobacco-inhaled products and obesity

"By 2030, more than 80 percent of the deaths will occur in developing countries, which have been increasingly targeted by tobacco companies seeking new markets to circumvent tightening regulation in developed nations." Tobacco use also brings an economic cost: WHO estimates that it drains more than $1.4 trillion (1.3 trillion euros) from households and governments each year in healthcare expenditures and lost productivity, or nearly two percent of the global gross domestic product