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Tobacco contains thousands of toxic chemicals that link to diseases of almost all organs, cancer heart disease lung conditions, including chronic obstructive pulmonary disorder (COPD) diabetes eye disease immune system difficulties rheumatoid arthritis tuberculosis Around 16 million people in the United States live with a smoking-related illness

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During crucial stages of brain development, nicotine exposure and endogenous cholinergic transmission alter cellular, physiological, and behavioral expression [66]

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