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Some of the major cellular responses to UVR, involving p53 activation, are depicted in Figure 2
This restoration could counteract the oncogenic effects of mutp53 and reinstate the tumor-suppressive properties of vitamin D in the skin
Ki67: 1:1000, abcam, ab92742, UK
[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Liebl M.C., Hofmann T.G
[DOI] [PubMed] [Google Scholar] 91.Mounessa J., Qin R., Dunnick C.A., Dellavalle R.P
In particular, different clinical trials (NCT00041613, NCT00041626) are underway using adenoviral p53 gene therapy in patients with recurrent SCC [120]
