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In a recent prospective 12-month randomized control design study (ECLAT study) we have just collected the data of E-cigs with 7.2 mg, 5.4 mg and 0 mg nicotine cartridges to measure smoking reduction or abstinence in 300 smokers unwilling to quit Declines in cig/day use and eCO levels were observed at each study visits in all three study groups (p,0.001 vs baseline), with no consistent differences among study groups

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It also decreases the dysphoria, depressed mood, that often occurs during nicotine withdrawal