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PMID 19112922

This is a bit of a softer medium blend due to the Maryland leaf which is very mild and a subtle air cured character but the Latakia seems very pronounced despite not dominating the blend components

This would accelerate the trend toward smoke-free products, leaving them with an ever-diminishing cigarette profit pool to cross-subsidise their activities in smoke-free products

Then, the overall risk of bias of each included study was evaluated as either: low (all criteria were of low risk), unclear (at least one criterion was evaluated to be of unclear risk but no criterion of high risk), or high (at least one criterion with high risk of bias)