glp 1 cardiovascular effects and Tolerability of GLP-1 Receptor Agonists: A Systematic Review and Meta-Analysis of 99,599 Patients Potential Mechanisms for Pro-Vascular Benefit
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Sometimes it is another factor entirely that has nothing to do with the medication

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For most healthy adults, yes

Tirzepatide is not appropriate for individuals with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

Hansen L, et al

That is why I tend to frame GLP-1 therapy as one tool within a broader system of care: medical evaluation, nutrition guidance, progressive exercise, load management, and when appropriate, a transition into structured strength training
