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Critical Reviews in Toxicology 42(1):68-89

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This study shows that not only does smokeless tobacco cause cancer, it can also affect a cancer patient's prognosis by increasing death risk (in this case, in prostate cancer patients)

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Factors Associated with Smoking Initiation and Cessation Natural history of tobacco use Tobacco use can be characterized as a chronic disease that begins in childhood because nearly all cigarette smokers report that they smoked their first cigarette during adolescence and then continue to use tobacco for decades.(46) Over 80% of U.S