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Since cigarette smoke is known to modulate expression and activity of the maintenance methyltransferase DNMT1, actively dividing cells may be more susceptible to exposure-mediated defects in DNA methylation
Weight and Body Fat: People who weigh more or with a higher body fat percentage may store and release Vyvanse metabolites differently than those with lower body weight or stored body fat Male or Female: Drug metabolism usually also varies between men and women

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However, because such hair testing methods are costly, they are not used as frequently as blood, saliva, or urine tests

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