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Moreover, administration of exendin-4 led to a reduction in 5-HT and 5-HIAA, whereas GLP-1R antagonists increased the levels of serotonin and its metabolites [56]

To view a copy of this licence, visit About this article Cite this article Zhang, L., Chen, X., Xu, Y

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While semaglutide can cause weight loss without lifestyle changes, NICE guidelines specify it should be used alongside diet and exercise modifications

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Following this, 32 articles were selected, and three abstracts were reviewed