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[25] [26] In 2012, Australia became the first country in the world to mandate standardized plain packaging intended to make cigarettes less appealing to new and existing smokers, especially adolescents and those focused on a personal brand image

Emphysema In an emphysema condition, the tobacco destroys the inner walls between the air sacs, causing the lungs air sacs (alveoli) to break down and creating bigger but fewer air sacs

A federal judge recently ruled the agency's mandate violates the Constitution

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Further high-quality, randomized controlled trials and rigorous observational studies are important to confirm findings from the research to date