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And because there is no evidence that IQOS reduces the risk for disease associated with smoking, the FDA rejected PMIs other request to market IQOS as a reduced risk product

doi: 10.1124/dmd.114.058008
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Cytisine does not exceed 30% of its plasma concentration in the brain, whereas nicotine, under similar conditions, reaches 65%

Heated Tobacco Products Heated tobacco is an alternative to smoking

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