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Laverne Smith, writing on MountVernon.org, observed that George Washington, like other large plantation owners, was dependent on tobacco to support his estate and position in society. It was the main source of income for decades at Thomas Jeffersons Monticello

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Its detection in urine may be possible with specific test kits [1]

Peer smoking and the nicotinic receptor genes: an examination of genetic and environmental risks for nicotine dependence

Genetic differences influence which individuals will develop a nicotine addiction upon initial use of the drug

Talk to your primary care physician about whether you should have a urinalysis