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7 in Cell Reports , the researchers identified specific genes and microRNA that play an essential role in how the roundworms develop nicotine dependence and withdrawal responsesclues that may carry over to the mammalian realm

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2013, 8: e57087-doi:10.1371/journal.pone.0057987 Bullen C, McRobbie H, Thornley S: Effect of an electronic nicotine delivery device (e cigarette) on desire to smoke and withdrawal, user preferences and nicotine delivery: randomised cross-over trial