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doi: 10.1007/s40259-013-0057-y 127 McCartyDColemanMBolandCL

Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: a Long March to Therapeutic Successes

Dose-dependent effects of the once-daily GLP-1 receptor agonist lixisenatide in patients with type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled trial

The specific dietary and exercise recommendations differ somewhat between the two drug classes
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Another goal of the study was weight loss, and the drug succeeded there, too: Participants on semaglutide lost about 13% of their body weight, compared with 2.6% for those on placebo, over the course of the year-long trial
