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[DOI] [PMC free article] [PubMed] [Google Scholar] [6].Jemal A, Torre L, Soerjomataram I, Bray F, The Cancer Atlas, Third edition ed., American Cancer Society, Atlanta, GA, 2019

However, the practice of ingesting the smoke from a smoldering leaf generates an enormous number of active chemical compounds, loosely lumped together as 'tar', many of which are biologically reactive and potential health dangers

This also promoted biofilm formation and handling with no cell loss, thus contributing to the maintenance of the biofilm structure