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In contrast, anti-inflammatory effects on immune cell populations would be reflected by reductions in fecal calprotectin and serum C-reactive protein (CRP) (15, 82)

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Diarrhea in 29.7 percent

Expired tirzepatide may have reduced potency or, in rare cases, contain degradation products that should not be injected

This is why stopping the medication during the early adjustment period (often the first month or two), when side effects are at their worst, often means missing the window in which the body would naturally adapt