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Previously, colchicine has been shown to provide anti-oxidative benefits [24, 25, 30], attenuate oxidative stress-induced DNA damage, impede pyroptosis and cellular senescence in endothelial cells [24, 26, 27]
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Finally, most studies were judged to be of high quality (305), with only a minority judged to be of moderate (101) or low (70) quality (Supplementary Table 2)